Seminars & Presentations

Date	Presenter Name	Talk Title	Annotation
3/3/2020	Jane Aldrich, PhD Professor Department of Medicinal Chemistry University of Florida College of Pharmacy	Novel opioid peptides that don’t follow the rules	Core A/School of Pharmacy
1/14/2020	Yaacov Barak, PhD Associate Professor of Obstetrics Department of Gynecology and Reproductive Science Magee-Women’s Research Institute	PPARgamma in Adipocytes: A master regulator of A survival factor?	Core A/School of Pharmacy
12/17/2019	Joshua Denny, MD Professor Vanderbilt University School of Medicine	The all of us research program and improving health through big data and engaging diverse populations	Core A/School of Pharmacy
11/5/2019	Shyni Varghese, PhD Professor of Bioengineering, Mechanical Engineering & Materials Sciences and Orthopaedics Duke University Pratt School of Engineering	Physicochemical properties of extracellular matrix: key to function, clue to mechanism	Core A/School of Pharmacy
9/17/2019	Wayne Backes, PhD Professor of Pharmacology LSU Health New Orleans School of Medicine	The role of protein-protein and membrane-protein interactions on the organization of P450 systems proteins	Core A/School of Pharmacy
7/23/2019	Sarah Harris, University of Leeds	Multiscale Simulations of Biological Macromolecules: from Atoms to the Continuum Limit	Seminar organized by Core B (DCSB)
4/16/2019	Minoli Perera, PharmD, PhD. Associate professor Department of Pharmacology Northwestern University	African Ancestry Pharmaco-omics	Seminar organized by Core A (school of pharmacy)
4/16/2019	Lillian Chong, University of Pittsburgh	The Art of Possibility: Weighted Ensembles of Trajectories	Seminar organized by Core B (DCSB)
4/2/2019	Dan Rosenbaum, PhD Associate professor Departments of Biophysics and Biochemistry UT Southwestern Medical Center	Structure and Mechanism of Human CNS GPCRs	Seminar organized by Core A (school of pharmacy)
3/26/2019	Patrick Marroum, PhD Senior Director& Senior Research Fellow Clinical Pharmacology and Pharmacometrics AbbVie Inc.	The Role of Modeling and Simulation in Setting Clinically Relevant Specifications	Seminar organized by Core A (school of pharmacy)
3/19/2019	Timothy P. Ryan, PhD Research Fellow Dyslipidemia and Outcomes Research Eli Lily and Company, Indianapolis, Indiana	Incorporating Genomic, Clinical, and Real-world Evidence Into Drug Discovery-perspectives and Future Directions	Seminar organized by Core A (school of pharmacy)
3/12/2019	Ali Saglam, University of Pittsburgh	Weighted ensemble sampling of rule-based models	Seminar organized by Core B (DCSB)
3/5/2019	Jane M. Liebschutz, MD, MPH, FACVP Chief, Division of General Internal Medicine Director, Center for Research on Health Care University of Pittsburgh School of Medicine	Approach to Opioid Use Disorder in General Medical Settings	Seminar organized by Core A (school of pharmacy)
3/29/2019	Florencio Serrano Castillo	Multi-Scale QSP Models of Cystic Fibrosis Airway Pathophysiology	Seminar organized by Core A
2/26/2019	Yuanyuan Chen, University of Pittsburgh	The Roles of Rhodopsin Homeostasis and Signaling	Seminar organized by Core B (DCSB)
2/12/2019	Weikang Wang, University of Pittsburgh	Single cell morphology trajectory analysis on cell cycle and Epithelial-to-Mesenchymal transition	Seminar organized by Core B (DCSB)
11/20/2018	John Schuetz, PhD Member, Vice Chair Department of Pharmaceutical Sciences St. Jude Children’s Research Hospital	ABC transporters as disease modifiers: Porphyria & cholestasis of pregnancy	Seminar organized by Core A (school of pharmacy)
12/18/2018	Olivier Lichtarge, Baylor College of Medicine	Making Personal Sense of Disease: Machine Learning and Mutational Calculus	Seminar organized by Core B (DCSB)
11/13/2018	HongChun Li, University of Pittsburgh	Improving Protein Sequence Matching to Aid Genome-Based Medicine	Seminar organized by Core B (DCSB)
11/6/2018	Yanqiao Zhang, MD, FAHA Professor Department of Integrative Medical Sciences Northeast Ohio Medical University	Role of miR-34a in cardiometabolic diseases	Seminar organized by Core A (school of pharmacy)
10/30/2018	Amy Newman, PhD Deputy Scientific Director Medication Development Program Chief, Molecular Targets and Medications Discovery Branch NIDA-IRP/NIH	Design of bitopic ligands with dopamine D2 receptor Bias	Seminar organized by Core A (school of pharmacy)
10/30/2018	Luca Ponzoni, University of Pittsburgh	Integrated Approach for Pathogenicity Prediction of Missense Variants	Seminar organized by Core B (DCSB)
10/30/2018	James Krieger, University of Pittsburgh	Normal Mode Sampling Simulations and Electron Microscopy Image Analysis	Seminar organized by Core B (DCSB)
10/16/2018	David Boulton, PhD Executive Director Quantitative Clinical Pharmacology AstraZeneca	The role of clinical pharmacology in drug development: Dapagliflozin, a novel SGLT2 inhibitor, as an example	Seminar organized by Core A (school of pharmacy)
10/2/2018	Kai Tan, PHD Associate Professor Department of Pediatrics and Department of Biomedical and Health Informatics The Children’s Hospital of Philadelphia University of Pennsylvania	Optimal control nodes in disease-perturbed networks as targets for combination therapy	Seminar organized by Core A (school of pharmacy)
5/22/2018	Ruiwen Zhang, MD, PhD, DABT, FAAAS Professor of Pharmacology and Toxicology Robert L. Boblitt Endowed Professor in Drug Discovery Director of UH Center for Drug Discovery	Targeting p53-MDM2 pathway: implication in cancer and neurogenerative diseases	Seminar organized by Core A (school of pharmacy)
4/25/2018	Velvet (Blair) Journigan, PhD Assistant Professor of Medicinal Chemistry Department of Pharmaceutical Sciences Marshall University School of Pharmacy	Structure-based design of novel small molecule ligands for the transient receptor potential melastatin 8 (TRPM8) ion channel: Insights and applications from recent structural biology advances	Seminar organized by Core A (school of pharmacy)
3/21/2018	Mary Torregrossa, PhD Assoc. Prof., Psychiatry, Translational Neuroscience Program, University of Pittsburgh	Identification of Novel Regulators of Cocaine-Associated Memories	New FRP
1/8/2018	Inmaculada Hernandez, PharmD, PhD Assistant Professor Department of Pharmaceutical Sciences University of Pittsburgh	Real-world Use, Outcomes, and (Value-based?) Pricing of Pharmaceuticals: An Overview of My Research Program	New P/FP
1/8/2018	Philip Empey, PharmD, PhD Assistant Professor Department of Pharmaceutical Sciences University of Pittsburgh	Pharmacogenomics to achieve precision medicine at Pitt/UPMC	New P/FP
12/11/2017	Andreas Pfenning, PhD Assistant Professor Department of Computational Biology Carnegie Mellon University	Interpreting addiction-associated genetic variation at regulatory elements	New FRP
11/10/2017	Min Xu, PhD Research Assistant Professor Department of Computational Biology Carnegie Mellon University	Structural mining in cellular electron cryo-tomograms	New P/FP
10/12/2017	Zachary Freyberg, PhD Assistant Professor Departments of Psychiatry and Cell Biology University of Pittsburgh	New Cryo-EM Approaches to the Study of Secretory Cell Biology	New P/FP
5/2/2017	Robert Roth, PhD, DABT Professor of Pharmacology and Toxicology Director, Graduate Program in Environmental and Integrative Toxicological Sciences Michigan State University	Drug-cytokine interaction in idiosyncratic, drug-delivered liver injury	Seminar organized by Core A (school of pharmacy)
4/24/2017	Xiaoyuan (Shawn) Chen, PhD Senior Investigator and Chief Laboratory of Molecular and Nanomedicine National Institute of Biomedical Imaging and Bioengineering National Institutes of Health	Nanomedicine for imaging and therapy	Seminar organized by Core A (school of pharmacy)
4/18/2017	Ram Mahato, PhD Professor and Chair Department of Pharmaceutical Sciences University of Nebraska Medical Center	Gene and stem cell therapy for improving islet transplantation in humanized mice	Seminar organized by Core A (school of pharmacy)
4/13/2017	Robert A. Sweet, MD UPMC Endowed Chair & Prof., Psychiatric Neuroscience and Neurology	Investigating the Mechanisms of Psychosis	New FRP
4/11/2017	Susan Slaugenhaupt, PhD Professor of Neurology Center for Human Genetic Research Massachusetts General Hospital Harvard Medical School	Developing a drug for an mRNA splicing disease	Seminar organized by Core A (school of pharmacy)
4/4/2017	Aiming Yu, PhD Professor Director of the PK/PD Bioanalytical Core Facility Department of Biochemistry and Molecular Medicine UC Davis School of Medicine	Translating microRNA pharmacoepigenetics into therapy	Seminar organized by Core A (school of pharmacy)
3/14/2017	Seth Corey, MD, PhD Professor and Chief Children’s Hospital Foundation Endowed Chair in pediatric Cancer Research Virginia Commonwealth University School of Medicine	Pediatric Myelodysplastic Syndromes: A Gain of Clones	Seminar organized by Core A (school of pharmacy)
3/3/2017	Howard Gutstein, PhD Peter & Eva Safar Prof. and Chair, Anesthiology, Upitt	Zero Tolerance for Chronic Pain	Seminar organized by Core A (school of pharmacy)
2/17/2017	Ming Hu, PhD Professor of Pharmaceutics University of Houston College of Pharmacy	Challenges facing CNS delivery of polyphenols and flavonoids	Seminar organized by Core A (school of pharmacy)
2/14/2017	Edward Prochownik, MD, PhD The Paul C. Gaffney Professor of Pediatrics and Professor of Microbiology & Molecular Genetics Section of Hematology/Oncology Rangos Research Center School of Medicine	Cancer as a Ribosomopathy	Seminar organized by Core A (school of pharmacy)
1/23/2017	Nicholas Meanwell, PhD Executive Director Department of Medicinal Chemistry Bristol-Myers Squibb Pharmaceutical Research and Development	NS5A inhibitors of hepatitis C	Seminar organized by Core A (school of pharmacy)
12/13/2016	Nathan A. Yates Associate Professor, Department of Cell Biology Scientific Director, Biomedical Mass Spectrometry Center Schools of the Health Sciences University of Pittsburgh	Application of Differential Mass Spectrometry for the Unbiased Identification of CSF Biomarkers and Novel Protein Targets	Seminar organized by Core A (school of pharmacy)
12/13/2016	Jacob D. Durrant, PhD Assistant Professor Department of Biological Sciences University of Pittsburgh	Computer-Aided Drug Design: From Basic Science to Clinical Applications	Seminar organized by Core A (school of pharmacy)
12/8/2016	Dandan Sun, MD, PhD Professor Department of Neurology School of Medicine University of Pittsburgh	Ion transporters: new targets for glioma therapy	Seminar organized by Core A
11/29/2016	Min You, PhD Professor Department of Pharmaceutical Sciences College of Pharmacy Northeastern Ohio Medical University	Lipin-1 signaling and its implications in the alcoholic fatty liver	Seminar organized by Core A (school of pharmacy)
11/8/2016	Dharini Shah, PhD Principal Scientist Center for Therapeutic Innovation Pfizer	Adventures in drug discovery: Case studies on immune checkpoint as therapies	Seminar organized by Core A (school of pharmacy)
11/1/2016	Edward A. Burton, MD, DPhil FRCP Associate Professor of Neurology, Microbiology and Molecular Genetics UPMC Endowed Chair in Movement Disorders School of Medicine University of Pittsburgh	Drug discovery for neurodegenerative diseases using novel zebrafish models	Seminar organized by Core A (school of pharmacy)
10/11/2016	Gavin Arteel, PhD Professor, Associate Chair for Research Department of Pharmacology and Toxicology University of Louisville School of Medicine	Transitional changes to the hepatic “matrisome” in the development of inflammatory liver injury	Seminar organized by Core A (school of pharmacy)
10/4/2016	Moses Turkle Bility, PhD Assistant Professor Department of Infectious Diseases and Microbiology Graduate School of Public Health University of Pittsburgh	Modeling human pharmacogenomics in humanized mice	Seminar organized by Core A (school of pharmacy)
9/27/2016	Dexing Zeng, PhD Professor, Molecular Imaging Laboratory Department of Medicine University of Pittsburgh	Dual-receptor targeting for enhance PET imaging	Seminar organized by Core A (school of pharmacy)
9/7/2016	Raman Venkataramanan, PhD Professor Dept. of Pharmaceutical Sciences, School of Pharmacy Dept. of Pathology, School of Medicine University of Pittsburgh	Modeling of PK and PD data in clinical pharmacology	Seminar organized by Core A (school of pharmacy)
8/8/2016	Christopher K. Surratt, Professor of Pharmacology, Mylan School of Pharmacy, Duquesne University	Do the behavioral effects of dopamine transporter (DAT) inhibitors correlate with DAT conformation preference?	Seminar organized by Core A (school of pharmacy)
8/8/2016	Kevin Xiao, Associate Professor, Department of Pharmacology and Chemical Biology, University of Pittsburgh	Defining the Higher Order Structures of GPCR Signaling Complexes for Drug Discovery	Seminar organized by Core A (school of pharmacy)
8/8/2016	Joshua Yohannan, MS, Laboratory Manager The Allegheny County Medical Examiner’s Office	AB vs ADB: One Methyl Makes a Large Difference	Seminar organized by Core A (school of pharmacy)
8/8/2016	Manojkumar Puthenveedu, Associate Professor, Biological Sciences and The Center for the Neural Basis of Cognition, Carnegie Mellon University	New strategies to manage opioid addiction and pain	Seminar organized by Core A (school of pharmacy)
8/8/2016	Sally E. Wenzel, Professor of Medicine & Director University of Pittsburgh Asthma Institute	b2-Adrenergic Receptor Responses and Asthma: Modulation through Protein-Lipid Interactions	Seminar organized by Core A (school of pharmacy)
8/8/2016	Youhua Liu, Professor, Department of Pathology, University of Pittsburgh	Targeting Cannabinoid Receptor-2 to Reduce Renal Fibrosis	Seminar organized by Core A (school of pharmacy)
8/8/2016	Rao Rapaka, Branch Chief of NIH NIDA	NIDA’s Basic Chemistry Research and Translational Areas of Interest	Seminar organized by Core A (school of pharmacy)
8/8/2016	Steven D. Shapiro, Executive Vice President, UPMC Chief Medical and Scientific Officer	UPMC’s Big Data Initiative	Seminar organized by Core A (school of pharmacy)
8/8/2016	Christopher Waller, Executive Director MRLIT Modeling Platformsand CORE Merck	Translational Data Science at Merck
8/8/2016	Avi Ma’ayan, Professor, Department of Pharmacology and Systems Therapeutics, Director of the Mount Sinai Center for Bioinformatics, Icahn Medical Institute	Mining LINCS Big Data to Knowledge
8/8/2016	Tarek A. Leil, Group Director Quantitative Clinical Pharmacology, Clinical Pharmacology & Pharmacometrics Exploratory Clinical and Translational Research (ECTR), Bristol-Meyers Squibb	Quantitative Systems Pharmacology (QSP) for Knowledge Integration and Hypothesis Generation in Pharmaceutical R&D	Seminar organized by Core A (school of pharmacy)
8/8/2016	Robert E. Kass Maurice Falk Professor of Statistics and Computational Neuroscience Interim Co-Director Center for the Neural Basis of Cognition Carnegie Mellon University	Statistical Thinking and Bayesian Thinking in Neuroscience	Seminar organized by Core A (school of pharmacy)
8/8/2016	Alexandros Makriyannis Professor George D. Behrakis Endowed Chair Director of the Center for Drug Discovery Northeastern University	Control the Deactivation of Cannabinergic Compounds	Seminar organized by Core A (school of pharmacy)
5/17/2016	Peter Blumberg, PhD. Chief, Molecular Mechanisms of Tumor Promotion Section Laboratory of Cancer Biology and Genetics National Cancer Institute, National Institutes of Health	Because it is never so simple, lessons from the phorbol esters	Seminar organized by Core A (school of pharmacy)
5/13/2016	Andreas Pfenning, PhD. Assistant Professor Computational Biology, Carnegie Mellon University	Genomic insights into the biological basis of behavior
4/26/2016	Alexander DÖmling, PhD. Professor and Chair Department of Drug Design, University of Groningen	Expanding chemical space with modern multi-component reactions towards small molecule PD1-PDL1 antagonists	Seminar organized by Core A (school of pharmacy)
4/19/2016	Brian Blagg, PhD. Professor of Medicinal Chemistry, University of Kansas	Modern Hsp90 inhibitors from old natural products	Seminar organized by Core A (school of pharmacy)
4/1/2016	Kunhong (Kevin) Xiao, PhD Associate Professor Pharmacology & Chemical Biology School of Medicine University of Pittsburgh	Proteomics and Systems Biology of GPCRs: Novel Paths to Drug Discovery	Seminar organized by Core A (school of pharmacy)
3/8/2016	Cheng Zhang, PhD. Assistant Professor Department of Pharmacology and Chemical Biology School of Medicine, University of Pittsburgh	GPCR structural pharmacology: Structures and Drugs	Seminar organized by Core A (school of pharmacy)
3/21/2016	Michael Zemaitis, PhD Professor Pharmaceutical Sciences School of Pharmacy University of Pittsburgh	The Current National and State-Wide Landscape of Medical Cannabis	Seminar organized by Core A (school of pharmacy)
1/12/2016	Milos Hauskrecht, PhD. Professor of Computer Science Department of Computer Sciences, University of Pittsburgh	Outlier detection for clinical monitoring and alerting	Seminar organized by Core A (school of pharmacy)
11/6/2015	Manojkumar Puthenveedu, PhD. Associate Professor Biological Sciences, Carnegie Mellon University	Opioid receptor trafficking – roles in opioid physiology and addiction	Seminar organized by Core A (school of pharmacy)
11/3/2015	Dexi Liu, PhD. Panoz Professor of Pharmacy, Head Department of Pharmaceutical and Biomedical Sciences College of Pharmacy, University of Georgia	Tuning-up gene expression to prevent and treat obesity and obesity-associated insulin resistance	Seminar organized by Core A (school of pharmacy)
10/13/2015	Xianghua Lu, MD, PhD. Associate Professor Department of Biomedical Informatics School of Medicine, University of Pittsburgh	Filling the gaps from cancer genome to personalized therapy: computational precision medicine	Seminar organized by Core A (school of pharmacy)
10/2/2015	Michael Vanyukov, PhD Professor Departments of Pharmaceutical Sciences, Psychiatry, and Human Genetics	Liability to Drug Addiction	Seminar organized by Core A (school of pharmacy)
9/29/2015	Dandan Sun, MD, PhD. Professor, Endowed Chair, Brain Disorder Research Department of Neurology School of Medicine, University of Pittsburgh	Fish oil DHA reduces ER stress in traumatic brain injury	Seminar organized by Core A (school of pharmacy)
9/11/2015	Mary Torregrossa, PhD. Assistant Professor Department of Psychiatry, Translational, Neuroscience Program, University of Pittsburgh	Identification of a Novel Regulatory Site on CaMKIIa Involved in Maintaining Cocaine Associated Memories	Seminar organized by Core A (school of pharmacy)
7/15/2015	Oscar L. Lopez, M.D. Departments of Neurology and Psychiatry School of Medicine, University of Pittsburgh	Long-Term Effects of Conbination therapy in Patients with Alzheimer’s Disease	Seminar organized by Core A (school of pharmacy)
5/14/2015	Mingfeng Bai, PhD. Assistant Professor Department of Radiology School of Medicine, University of Pittsburgh	Development of a CB2-selective Near Infrared Fluorescent Probe	Seminar organized by Core A (school of pharmacy)
5/14/2015	Ethan Block, PhD. Department of cell biology University of Pittsburgh	Regulation of dopamine transporter function by classical and predicted ligands	Seminar organized by Core A (school of pharmacy)
5/14/2015	Ralph E. Tarter, PhD. Professor Pharmaceutical Sciences, University of Pittsburgh	Lifespan Perspective of Drug Addiction	Seminar organized by Core A (school of pharmacy)
5/14/2015	Mary Torregrossa, PhD. Assistant Professor Department of Psychiatry, University of Pittsburgh	Development of Ligands for Memory-Based Treatments for Addiction	Seminar organized by Core A (school of pharmacy)