XieXiang-Qun (Sean) Xie, Ph.D.,EMBA (Director of CDAR and PI of Core A)
Professor of Pharmaceutical Sciences/Drug Discovery Institute
Director of Computational Chemical Genomics Screening Center
Director of NIH NIDA Center of Excellence for Computational Drug Abuse Research
Associate Dean for Research Innovation, School of Pharmacy, University of Pittsburgh

 

Lirong Wang, Ph.D. (Admin and Coordinator of Core A)
Assistant Professor
Pharmaceutical Sciences, University of Pittsburgh

Dr. Wang’ research interest: Chemogenomics/Chemoinformatics database, Structure-based and Ligand-based drug design, Bioinformatics database, Signaling pathway, Data mining & Machine learning algorithms

 

Zhiwei Feng, Ph.D.
Assistant Professor
Pharmaceutical Sciences
University of Pittsburgh

 

 

Ziheng Hu
PhD Student
Pharmaceutical Sciences, University of Pittsburgh

Ziheng’s research interests include the application of advanced statistical methods and machine learning algorithms on clinical data analysis. Currently, his research focuses on establishing a clinical decision support system to facilitate personalized medicine for Alzheimer’s disease patients with various comorbidities.

 

Shifan Ma
PhD Student
Pharmaceutical Sciences, University of Pittsburgh

Shifan’s research interests focus on computational-aided medicinal chemistry, including molecular docking, pharmacophore, similarity search, design, synthesis and in vitro bio-assay evaluations, predicting targets for natural products, virtual screening.

 

Changrui Xing
PhD Student
Pharmaceutical Sciences, University of Pittsburgh

Changrui’s research interests include: 1) Structural biology and pharmacology of Cannabinoid receptor 2 (CB2). 2) Design, optimization, and validation of CB2 novel agonists and inverse agonists. 3) Molecular mechanism of CB2.

 

Yuemin Bian
PhD Student
Pharmaceutical Sciences, University of Pittsburgh

Yuemin’s research interests include the study of GPCR allosteric regulation with multiple in silico methodologies, ranging from molecular dynamic simulations, molecular docking, protein modeling, etc. He is focused on using computational fragment-based approach for designing allosteric modulators on the cannabinoid receptor 2, which may exhibit treatment benefits on drug abuse.

 

Yankang Jing
PhD Student
Pharmaceutical Sciences
University of Pittsburgh

 

 

Nanyi Wang
Master Student
Pharmaceutical Sciences
University of Pittsburgh

 

Zhaojia Zhang
Master Student
Pharmaceutical Sciences
University of Pittsburgh

 

 

Hongjuan Bao, PhD
Visiting Scholar

Dr. Bao’s research focus on GBM chemogenomics knowledgebase for systems pharmacology research. Study on material foundation and mechanism of Chinese herbs based on Computer aid drug design and systems pharmacology.

 

 

Haixia Ge, PhD
Visiting scholar

Dr. Ge’s research interests is computational-aided medicinal chemistry, including molecular docking, pharmacophore, design, synthesis and in vitro bio-assay evaluations.