Journal Clubs

  • Weekly literature review presentations within each Core
  • Additional events with FRP investigators
  • Presentation opportunity for students, trainees, & postdocs
Date Presenter Name Talk Title
3-21-18 Mary Torregrossa,

Assoc. Prof., Psychiatry, Translational Neuroscience Program, UPitt

“Identification of Novel Regulators of Cocaine-Associated Memories.”New FRP
1-8-18 (Inma) Hernandez, PharmD, PhD

Assist. Prof., Pharm. Sci., UPitt

“Real-world Use, Outcomes, and (Value-based?) Pricing of Pharmaceuticals: An Overview of My Research Program.”

New FRP

1-8-18 Philip Empey, PharmD, PhD

Assist. Prof., Pharm. Sci., UPitt

“Pharmacogenomics to achieve precision medicine at Pitt/UPMC.”

New FRP

12-11-17 Andreas Pfenning, PhD, Assist. Prof., Computational Biol., CMU “Interpreting addiction-associated genetic variation at regulatory elements.”New FRP
11-10-17 Min Xu, PhD

Res. Assist. Prof., Computational Biol., CMU

“Structural mining in cellular electron cryo-tomograms”

New FRP

10-12-17 Zachary Freyberg, PhD

Assist. Prof., Psychiatry and Cell Biology, UPitt

“New Cryo-EM Approaches to the Study of Secretory Cell Biology”

New FRP

9-22-17 Yuemin Bian

Grad Student (Core A)

“Computational chemogenomics-based targets identification and protein binding modes analysis for cannabidiol.”
9-22-17 Junmei Wang, PhD

Assoc. Prof., Pharm. Sci. (Core A)

“Physics-based scoring function development and theirs applications on modeling protein-ligand interactions.”
5-5-17 Haohan Wang

Grad Student (Core C)

“Spectral Linear Mixed Model, accounting for complicated population

structures in association studies”

5-5-17 Haohan Wang

Grad Student (Core C)

“Discovering Weaker Genetic Associations with Validated Association,

with Studies of Alzheimer’s Disease and Drug Abuse Disorder”

4-13-17 Jiyoung Lee, PhD

Research Assoc. (Core B)

“Anisotropic network modeling (ANM) analysis of b-arrestin-1”
4-13-17 Robert A. Sweet, MD

UPMC Endowed Chair & Prof., Psychiatric Neuroscience and Neurology

“Investigating the Mechanisms of Psychosis”

 

3-3-17 Nanyi Wang

Grad Student (Core A)

“ProSelection: A novel program to pick optimal protein structure subsets for in silico target identification and drug discovery research.”
3-3-17 Howard Gutstein, PhD

Peter & Eva Safar Prof. and Chair, Anesthiology, UPitt

“Zero Tolerance for Chronic Pain”

 

2-17-17 Ben Lengerich

Grad Student (Core C)

“Improving the Accuracy of Genome-Wide Association Studies”
2-17-17 Haohan Wang

Grad Student (Core C)

“Genomic Research with Validated Association”
1-19-17 Bing Liu, PhD

Research Assoc. (Core B)

“Systems-level insights into cellular regulation from quantitative modeling and analysis”
1-19-17 Mary Hongying Cheng, PhD

Res. Assist. Prof. (Core B)

“Molecular-level mechanisms of transporters and ion channels”
12-8-16 LiRong Wang, PhD

Assist. Prof. (Core A)

“Pharmacogenomics study of synthetic cannabinoid intoxication.”
12-8-16 Dandan Sun, MD, PhD 

Prof., Neurology, UPitt

“Ion transporters: new targets for glioma therapy.”

 

11-4-16 Bryon Aragam, PhD

Post-doc (Core C)

“Reconstructing Biological Networks with Structural Equations – A New Machine Learning Approach to Better Understanding Drug Abuse”
10-5-16 Cihan Kaya

Grad Student (Core B)

“Dynamics of Dopamine Transporters: Bridging Molecular and Cellular Simulations”
10-5-16 Jiyoung Lee, PhD

Research Assoc. (Core B)

“Update on Gamma-Secretase Project”
9-7-16 Yuemin Bian

Grad Student (Core A)

“Computational Fragment-based Approach for the Discovery of Allosteric Modulators on Metabotropic Glutamate Receptor 5.”
9-7-16 Hongfei Zhang

Grad Student

“Modeling of PK and PD data in clinical pharmacology.” (part 3)
9-7-16 Rujuta Joshi

Grad Student

“Modeling of PK and PD data in clinical pharmacology.” (part 2)
9-7-16 Raman Venkataramanan, PhD

Prof., Pharm. Sci. and Pathology

“Modeling of PK and PD data in clinical pharmacology.” (part 1)

 

4-1-16 Jiyoung Lee, PhD

Research Assoc. (Core B)

“ANM analysis of intact gamma-secretase with membrane”
4-1-16 Filippo Pullara, PhD

Res. Associate (Core B)

“Combined computational and experimental study of CamKII”
4-1-16 Bing Liu, PhD

Research Assoc. (Core B)

“Computational Modeling of the Amphetamine-induced Regulation of Dopamine Transporters”
3-21-16 Yan Zhang

Grad Student (Core A)

“Mathematical Model of Cannabinoid Receptor Type 2 Endocytosis and Trafficking”
3-21-16 Ziheng Hu

Grad Student (Core A)

“Big data” type data mining effect of anti-hypertensive and anti-diabetic drugs on cognitive decline in Alzheimer’s disease patients”
3-21-16 LiRong Wang, PhD

Assist. Prof., Pharm. Sci., UPitt (Core A)

“Utilizing transcriptional data for brain disease and drug research.”
2-   -16 Micol Marchetti-Bowick

Grad Student (Core C)

“A Penalized Regression Model for the Joint Estimation of eQTL Associations and Gene Network Structure.”
2-   -16 Siwei Xie

Grad Student (Core C)

“Analysis of Gene Expression Patterns induced by Drugs of Abuse in Mouse Striatum.”
1-8-16 Bing Liu, PhD

Research Assoc. (Core B)

“Integrative Analysis of Lipoxygenase Pathways in Asthma”
1-8-16 HongChun, Li

Post-doc Assoc

(Core B)

“BalestraWeb server”
1-8-16 Jiyoung Lee, PhD

Research Assoc. (Core B)

“ANM analysis of gama-secretase”
12-4-15 Peng Yang, PhD

Res. Assist. Prof.

Pharm. Sci., UPitt

“Cannabinoid CB2 ligand Design”

 

12-4-15 Zhiwei Feng, PhD

Post-doc (Core A)

“Computer Modeling of 3D Structures of Cannabinoid Receptor Subtype CB2 activated through G-protein Coupling Process”
12-4-15 Yan Zhang

Grad Student (Core A)

“Modeling Simulation on Cannabinoid Receptor CB2 Signaling Pathway via Desensitization and Resensitization”
11-6-15 Georg Schoenherr

Grad Student (Core C)

 

Min Kyung Lee

Research Scientist, Center for Machine Learning, CMU

“How to use the GenAMap software system.”
10-2-15 Jiyoung Lee, PhD

Research Assist. (Core B)

“Tutorial for Anisotropic Network Model Web Server: Global Motion of Protein.”
9-11-15 Filippo Pullara, PhD

Res. Associate (Core B)

“CaMKII/Calmodulin binding under oxidative stress conditions: Synergy of Experiments and Computer Simulations approaches”
9-11-15 Mustafa Tekpinar, PhD

Visiting Scholar (Core B)

“Investigating dynamics of CamKII by elastic network models”
9-11-15 Ziheng Hu

Grad Student (Core A)

Unraveling the intricate role of anti-hypertensive and anti-diabetic medications in Alzheimer’s disease.” (Collaboration with Dr. Oscar Lopez, ADCR Center)
9-11-15 Zhiwei Feng, PhD

Post-doc (Core A)

“Diarylurea Small Molecule Inhibitors of TRPV1 as Potential Therapeutics for Neuroinflammation.”